Richard Manderville, Canada

Richard Arnold Manderville, PhD

Department of Chemistry
Science Complex, Rm 3243
Guelph, ON, Canada N1G 2W1
e-mail: rmanderv@uoguelph.ca

Education

  • Institution and Location, Degree, Year, Field of Study
  • Queen’s Univ., Kingston, Canada, B.Sc., 1986, Biology & Chemistry
  • Queen’s Univ., Kingston, Canada, Ph.D, 1992, Chemistry
  • Univ. of Virginia, Charlottesville, USA, Postdoc, 1995, Chemistry

 

Representative Publications:

  • Sproviero, M. Verwey, A.M.R.; Rankin, K.M.; Witham,A.A.; Soldatov, D.V.; Manderville, R.A.; Fekry, M.I.; Sturla, S.J.; Sharma, P.; Wetmore, S.D. Nucleic Acids Res. 2014, 42, 13405.
  • Sharma, P.; Manderville, R.A.; Wetmore, S.D. Nucleic Acids Res. 2014, 42, 11831. 
  • Sproviero, M.; Manderville, R.A. Chem. Comm. 2014, 50, 3097. 
  • Sproviero, M.; Rankin, K.M.; Witham, A.A.; Manderville, R.A. J. Org. Chem. 2014, 79, 692.
  • Sproviero, M.; Fadock, K.L.; Witham, A.A.; Manderville, R.A.; Sharma, P.; Wetmore, S.D. Chem. Sci. 2014, 5, 788.
  • Kuska, M.S.; Witham, A.A.; Sproviero, M.; Manderville, R.A.; Majdi Yazdi, M.; Sharma, P.; Wetmore, S.D. Chem. Res. Toxicol. 2013, 26, 1397. 
  • Kuska, M.S.; Majdi Yazdi, M.; Witham, A.A.; Dahlmann, H.A.; Sturla, S.J.; Wetmore, S.D.; Manderville, R.A. J. Org. Chem. 2013, 78, 7176.
  • Sharma, P.; Manderville, R.A.; Wetmore, S.D. Modeling the Conformational Preference of the Carbon-Bonded Covalent Adduct Formed upon Exposure of 2′-Deoxyguanosine to Ochratoxin A. Chem. Res. Toxicol. 2013, 26, 803–816.

 

Theses (Last 3 years):

  1. Aaron, A. Witham, PhD, 2014, “Structural Analysis of Detrimental Oxidative Products from Phenolic Carcinogens and Construction of Nucleotide Tools from Analogous Processes
  2. Michael Sproviero, PhD, 2014, “Characterization of Fluorescent 8-Aryl-Guanine Mimics: From Mutagenic Lesions to Probes for Aptasensor Development
  3. Florence D. Berger, MSc, 2013, “Synthesis and Properties of Duplex DNA Containing Oxygen-Linked Deoxyguanosine Adducts Derived from Phenolic Carcinogens” (Collaboration with the ETH, Zurich, Switzerland).
  4. Michael S. Kuska, MSc, 2013, “Structure and Stability of Oxygen-Linked DNA Adducts Derived From Phenolic Toxins
  5. Katherine M. Rankin, PhD, 2012, “Structure and Properties of C8-Aryl-2′-Deoxyguanosine Adducts: From Mutagenic Lesions to Conformational Probes in Duplex DNA

 

Collaborators:

  1. Stacey D. Wetmore, Department of Chemistry, University of Lethbridge, Alberta, Canada
  2. Shana Sturla, Institute of Food, Nutrition and Health, ETH, Zurich, Switzerland 

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CESAR 2015

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