Odilorhabdins are produced by a symbiotic bacterium found in soil-dwelling nematode worms.
Called Xenorhabdus nematophila, the bacterial symbiont produces toxins and immuno-modulators, enabling the nematode to colonize and kill insects. The bacteria further benefit the host nematode by releasing antibiotics that prevent the invasion of the insect’s carcass by other competing bacteria and fungi.
To identify the antibiotics, University of Illinois scientists and their colleagues from Nosopharm, a biotechnology company based in Lyon, France, screened 80 cultured strains of the bacteria for antimicrobial activity.
The researchers then isolated the active compounds, studied their chemical structures and engineered more potent derivatives.
They found that odilorhabdins act on the ribosome — the molecular machine of individual cells that makes the proteins it needs to function — of bacterial cells.
Read more here or in original scientific article published in the journal Molecular Cell.
Osnovna svrha projekta je doprinijeti uvođenju, razvoju i održivosti programa društveno korisnog učenja na fakultetima. Više o projektu
Cilj Društva je okupljanje mikrobiologa i stručnjaka srodnih struka s ciljem unapređenja svih grana mikrobiologije.
Date: 25-28 September 2024
Venue: Zadar, Croatia
We are honoured and pleased to invite you to the second international symposium “Power of Viruses 2024” to be held at the Hotel Kolovare, Zadar, Croatia, 25-28 September 2024.Ovaj sveučilišni priručnik napisalo je petnaestak autora iz desetak visokoškolskih ustanova iz Zagreba i Rijeke, a sadržaj je podijeljen u petnaest, slikama bogato ilustriranih poglavlja u kojima su opisane i obrađene različite bakteriološke, virološke, mikološke, imunološke i molekularno-biološke metode koje se upotrebljavaju u općoj mikrobiologiji koja se studira na nizu različitih fakulteta i visokih škola.
Radi se o vrhunskoj literaturi za potrebe visokoškolske nastave iz veterinarske imunologije. Knjiga je svojim sadržajem namijenjena prvenstveno studentima, ali i veterinarima u praksi i nastavnicima.
(Iz recenzije)